ABSTRACT Noise is a disturbing sound that has temporary or permanent effects on the hearing system. Noise-induced hearing loss is the most important cause of hearing loss in adults, but it is also one of the most common occupational diseases. Understanding the pathophysiology of noise and its effects on the auditory system is crucial to prevent these losses. In line with this information, the study aims to systematically compile studies investigating the pathophysiology of noise and its effects on the auditory system.