ISSN: 2687-5349 / E-ISSN: 2687-5411 / PERIOD: Quarterly / YEAR OF START: 2019 / PUBLISHER: Istanbul Yeni Yuzyil University

Yeni Yüzyıl
Journal of Medical Sciences

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"Dear colleagues, Fentanyl, this well-known analgesic drug was synthesized in early 50’s and used from then on. It is a synthetic opioid that is up to 50 times stronger than heroin and 100 times stronger than morphine. I wanted to bring to your attention the alarming issue surrounding the misuse and abuse of fentanyl globally. The rise in fentanyl-related incidents is deeply concerning and requires immediate attention. As we navigate these challenging times, it's crucial for us to collectively raise awareness about the dangers of fentanyl and work towards implementing preventive measures. Whether through educational programs, community outreach, or policy initiatives, it is our responsibility to tackle this problem head-on. By fostering open conversations and promoting understanding, we can contribute to a safer and healthier community. Together, we can make a meaningful impact and protect the well-being of our community. Dear colleagues, This is the last JMS issue that I will be the editor of that is why I wanted to mention about this danger once it is related to my area of expertise. As I bid farewell to this chapter of my journey, I want to express my deepest gratitude for the incredible experiences, shared moments, and valuable lessons learned during our time together with all my collaborators. Working alongside such talented and dedicated individuals has been an honor and a source of inspiration. I will undoubtedly miss the warmth and camaraderie of this amazing team. Thank you for being a part of my journey. Wishing continued success for our JMS Warm regards,

ARTICLES

Milenyum Öncesi Travma Yönetiminde Yaşananlar-Houston Çalışması

Trauma is one of the leading causes of death in young adults and children. Among the exogenous factors leading to trauma-related mortality are damage occurring within the first hour, and causes secondary to resuscitation and surgery. As a result of the experiences gained, the concept of the 'golden hour' emerged, which defines the period in which life can be saved with appropriate medical intervention in the early stages of trauma. Significant progress has been made with the contribution of developing technology and advanced imaging methods in order to evaluate gold watches correctly.

Authors: Abuzer ÖZKAN

Page Number: 31-31

Mechanical Analysis of 3D Printed Biocomposite AFOs

Aim: The aim is to produce custom Ankle Foot Orthoses (AFO) with biocompatible materials compared to traditional orthotic manufacturing materials, perform tensile strength analysis, and compare them with traditional AFOs. Methods: Initially, traditional AFO materials were subjected to a tensile test. Following the test information, materials demonstrating similar tensile strength were researched, and biocomposite filaments with different mixture ratios of Polylactic acid (PLA) / Polycaprolactone (PCL) were obtained. Mechanical test specimens were produced from the filaments using a 3-dimensional printer.

Authors: Bahadır BOZKURT, M. Hüsnü DİRİKOLU

Page Number: 22-30

Investigation Of The Effects Of Biomaterials Used In Cranioplasty On Radiotherapy Dose By The Monte Carlo Method

Aim: The gold standard in the treatment of brain tumors is radiotherapy and chemotherapy after surgery. Radiotherapy with high-energy ionizing radiation after surgery has an important place in the treatment of brain tumors. Implants with a high atomic number exhibit strong radiation attenuation and scattering properties that could potentially compromise the delivery of radiation therapy by distorting the dose distribution in and around the implant volume, complicating treatment planning in radiotherapy.

Authors: Meryem Cansu ŞAHİN, Gökçe Nur GÜNDÜZ, Kaan CİYERCİ, Ali TEKE, Batuhan YILDIZ

Page Number: 16-21

Galatins and Stomach Cancer

Gastric cancer is a heterogeneous type of cancer that shows histopathological and epidemiological differences in various countries and is common throughout the world. Gastric cancer may be caused by microbial factors such as Helicobacter pylori and Epstein-Barr virus (EBV) infections, genetic factors including family history, A blood group, E-cadherin gene mutation, and environmental factors such as smoking, alcohol, consumption of foods high in fat, carbohydrate, nitrate, and salt.

Authors: Ayşe AKSU, İlhan YAYLIM

Page Number: 8-15

SLAMF7: A Novel Cancer-Related Target Molecule

Cancer is characterized by a wide variety of complex processes that yield uncontrolled growth for the cell. These complex processes must be elucidated to achieve goals such as early disease detection, improving prognosis, survival time, and chances of cure. It is, therefore, important to understand how and why cancer starts and how metastasis and recurrence occur. Biomarkers determine the presence, type, and aggressiveness of cancer cells and help in the selection of personalized, targeted therapeutic agents.

Authors: Seda BULUT, İlhan YAYLIM

Page Number: 1-7

31 JULY 2024

Volume:5 Issue:3 is published.