Trauma is one of the leading causes of death in young adults and children. Among the exogenous factors leading to trauma-related mortality are damage occurring within the first hour, and causes secondary to resuscitation and surgery. As a result of the experiences gained, the concept of the 'golden hour' emerged, which defines the period in which life can be saved with appropriate medical intervention in the early stages of trauma. Significant progress has been made with the contribution of developing technology and advanced imaging methods in order to evaluate gold watches correctly.
Aim: The aim is to produce custom Ankle Foot Orthoses (AFO) with biocompatible materials compared to traditional orthotic manufacturing materials, perform tensile strength analysis, and compare them with traditional AFOs.
Methods: Initially, traditional AFO materials were subjected to a tensile test. Following the test information, materials demonstrating similar tensile strength were researched, and biocomposite filaments with different mixture ratios of Polylactic acid (PLA) / Polycaprolactone (PCL) were obtained. Mechanical test specimens were produced from the filaments using a 3-dimensional printer.
Aim: The gold standard in the treatment of brain tumors is radiotherapy and chemotherapy after surgery. Radiotherapy with high-energy ionizing radiation after surgery has an important place in the treatment of brain tumors. Implants with a high atomic number exhibit strong radiation attenuation and scattering properties that could potentially compromise the delivery of radiation therapy by distorting the dose distribution in and around the implant volume, complicating treatment planning in radiotherapy.
Gastric cancer is a heterogeneous type of cancer that shows histopathological and epidemiological differences in various countries and is common throughout the world. Gastric cancer may be caused by microbial factors such as Helicobacter pylori and Epstein-Barr virus (EBV) infections, genetic factors including family history, A blood group, E-cadherin gene mutation, and environmental factors such as smoking, alcohol, consumption of foods high in fat, carbohydrate, nitrate, and salt.
Cancer is characterized by a wide variety of complex processes that yield uncontrolled growth for the cell. These complex processes must be elucidated to achieve goals such as early disease detection, improving prognosis, survival time, and chances of cure. It is, therefore, important to understand how and why cancer starts and how metastasis and recurrence occur. Biomarkers determine the presence, type, and aggressiveness of cancer cells and help in the selection of personalized, targeted therapeutic agents.