Aim: Uveitis is an inflammatory disease of the middle layer
of the eye, and the most common form is anterior uveitis.
It has been observed that almost half of the anterior uveitis
cases may be idiopathic in origin. Many systemic diseases
are associated with the oral cavity. Periodontal diseases are
often at the forefront of discussions, particularly in relation
to their significant impact on overall health. The term uveitis
has been regarded as a primary focus in previous studies on
the oral cavity. This discussion focuses on cardiovascular conditions,
pregnancy, and diabetes. We believe that evaluations
should be considered not only under the disease’s main title,
but also according to the anatomy, disease factor, and clinical
duration. Therefore, it was thought that this subject should
be re-examined, considering the growing knowledge and classifications
that have become widespread. The current literature
generally belongs to earlier periods and includes only a
few recent studies and case reports. Thus, this study aims to
investigate possible periodontal-dental factors in a group of
patients with idiopathic anterior uveitis.
Material- Methods: Thirty patients [15 patients with idiopathic
anterior uveitis-study group (SG): 7 female-8 male; 15
healthy control group (CG): 8 female-7 male] were included
in this pilot study. For each individual, the gingival index
(GI), plaque index (PI), probing depth (PD), and clinical attachment
level (CAL), which are used in routine periodontal
examination and help to determine periodontal status, were
measured. The decayed-missing-filled teeth index (DMFT)
was recorded to reveal their current dental status. Mucosal
changes (ulceration, hyperplasia, etc.) and abnormal conditions,
if any, were noted in the individuals. This study investigated
possible differences in periodontal-dental parameters between the SG and CG groups. In statistical evaluations, a
p-value of <0.05 was accepted as significant.
Results: The mean PI, PD, and CAL values were significantly
higher in the SG (p<0.05). GI and DMFT indices failed to
show any differences between SG and CG.
Conclusion: Current research is exploring the potential connection
between idiopathic anterior uveitis and various periodontal
parameters. Preliminary findings suggest that there
may indeed be a relationship worth investigating further.
Aim: Errors that occur occasionally in medical practices can
sometimes lead to irreversible consequences. While there is
an inherent level of risk and a margin for error in healthcare,
these should be minimized as much as possible. Sometimes,
news about the implications of medical errors on social media,
along with situations that individuals have either experienced
or observed, can make people anxious about these
mistakes. In this study, patients were surveyed about medical
malpractice, and their responses were analyzed.
Methods: Quantitative research was conducted using online
and face-to-face survey techniques and the data was obtained
from people who voluntarily agreed to participate in
the study. The population of the study is individuals over the
age of 18 who have received health services in Turkey. The
research sample consists of 400 participants and the questionnaire
form used in the study consists of three parts. The first
part includes demographic data and statements about medical
malpractice; in the second and third parts, the questionnaire
forms consisting of eight judgment statements to determine
the approach towards medical error and reasons for
medical error, composed of eight judgment statements, which
the researcher finalized by using the scale developed by Bilgin
and Others (2019) and the statements used by Er and Cezlan
(2022) in their research and taking the opinions of experts,
was used. Frequency and percentage analysis techniques and
chi-square tests were used in the analysis.
Results: Most of the 400 participants were male. The education
levels were primarily associate degrees and bachelor's
degrees. Nearly two-thirds of the participants reported that
they are familiar with medical malpractice. However, the majority
believe they have not personally experienced medical
malpractice.
Conclusion: The study revealed that most patients reported understanding a medical error but often confused it with
complication. Participants believe that most medical errors
can be prevented. Given the study's results, organizing public
service announcements and training sessions is essential to
increase awareness of medical errors and complications.
Nutritional behavior during pregnancy and lactation has
a lifetime effect on the offspring phenotype and metabolism.
Maternal energy, protein, and micronutrient intake
may cause changes in the fetal epigenome. Epigenetic
changes that affect gene expression and the lifelong health
of the fetus are mediated by DNA methylation, histone
modifications, and non-coding RNA (ncRNA). Maternal
excess energy and/or insufficient protein intake may lead
to metabolic diseases such as obesity, glucose intolerance,
and insulin resistance in the offspring later in life. Inadequate
intake of folate, B12, choline, and betaine, which are
methyl donors and cofactors in one-carbon metabolism,
causes low birth weight and decreased cognitive functions
of the offspring, while increased homocysteine (Hcy) levels
lower psychomotor scores in infants. It also shows a
higher risk of psychological problems in childhood, as
well as neurotoxic, vasculotoxic, and teratogenic effects.
This study will discuss the effects of maternal nutrient
intake on epigenetic mechanisms and present a perspective
on the effects of maternal methyl donor intake on offspring
health.
The Pancreas, a vital organ due to its production of digestive
enzymes and regulatory hormones, can be affected by
various endocrine and exocrine diseases, including cancer.
Pancreatic cancer (PC), which has the lowest 5-year
survival rate of approximately 10% among major organ
tumors, is an aggressive, late-diagnosed, poor-prognosis
type of cancer. PC typically remains asymptomatic until
the advanced stage in most patients, making it challenging
to reheat. Surgery remains the sole treatment modality
with the potential for curative outcomes; however, it is
applied only to a small percentage of patients. The risk
of PC has been affirmed due to the rise in daily cigarette
consumption and smoking duration, whereas quitting
smoking yields the contrary effect. Moreover, factors such
as higher body mass index, longer-term obesity, history
of pancreatitis, excessive alcohol consumption, diabetes,
and impaired fasting glucose are all linked to an increased
risk of PC. Increasing awareness of genetic predisposition
and avoiding such risk factors may significantly help in
reducing this disease’s prevalence in society. In addition
to conducting extensive research on treatment options,
studying modifiable risk factors that help limit PC development
is crucial. This review examines recent studies on
these risk factors and evaluates their distribution in Turkey.
Our analysis suggests—even when other factors are
not considered—that the rising rates of obesity, diabetes,
and smoking (modifiable risk factors) are likely to lead to
an increase in the prevalence of PC in Turkey in the coming
years.
